Endocrine Abstracts

Background: Procalcitonin (PCT) is often an increased acute phase reactant in the bacterial infection-related inflammation, and its serum level is reported elevated in several autoimmune disease. However, the level of PCT and its relationship with autoimmunity remain unknown in Hashimoto’s thyroiditis (HT). Our objective was to investigate the serum levels of PCT and its association with autoantibodies in patients with euthyroid HT.Methods: A total ...

Introduction: Graves’ disease and Hashimoto’s hypothyroidism are common thyroid diseases. However, occurrence of both clinical disorders one after the other in the same patient, is not common.Case report: In this article, we presented two hypothyroid patients who developed clinical thyrotoxicosis during levothyroxine treatment. Both patients were treated with levothyroxine for a long time. Due to occurrence of clinical hyperthyroidism, levothyr...

Introduction: Primary hyperparathyroidism (PHP), is generalized with calcium, phosphate, and bone metabolism disorder due to increased PTH secretion. It’s common in fifth and sixth decades. Nowadays, it’s widely detected by measurement of blood calcium and may be presented with minimal or no symptoms.Design: 102 patients with PHP admitted to Department of Endocrinology, between years of 2008–2013 were analyzed.Result...

Background: Bronchial Asthma is characterized by inflammation and airway hyperesponsiveness, which results in episodic airflow obstruction. A relationship between inflammation and insulin resistance has been previously noted and asthma is known to correlate with insulin resistance.Aim: The aim of this study is to evaluate the prevalence of asthma in type 2 DM patients,presented in ‘IKEDA’ Hospital, in the period of time January 2010–Decemb...

Introduction: We present a case investigated due to hypokalemia and diagnosed as rectal neuroendocrine tumor-related EAS.Case: A 67-year-old woman with weight loss and symptoms of lethargy, abdominal pain was referred due to low serum K+ levels. Elevated blood pressure and a rectal mass were detected at physical examination. Low serum K+, elevated ALT levels, lymphopenia, neutrophilia and metabolic alkalosis were present. Computed t...

Background and Aim: Prolactinoma is the most common type of functional pituitary tumor in adults. Giant prolactinomas are defined as tumors achieve a diameter >4 cm and often have very high serum prolactin level. In our previous study showed that endoscopic endonasal pituitary surgery is a very convenient procedure for the patient due to low morbidity and high efficiency. In this study we evaluated endoscopic endonasal pituitary surgery series in patients with prolactinoma...

Imaging in paragangliomas can be challenging as they arise from a number of locations including the adrenals, abdomen, pelvic and thoracic sites of chromaffin sympathetic tissue. They can also arise in the head and neck at sites of parasympathetic tissue. They are considered within the group of heterogenous neuroendocrine tumours. In addition to manifesting at multiple sites, they can metastasise, have variable expression of catecholamines and can be a manifestation of heredit...

A 34-year-old African woman presented with a 4-month history of profound lethargy, weight loss and a 3-day history of vomiting, fever, confusion, and drowsiness. She had given birth to her third child 6 months previously. Her pregnancy and delivery were uncomplicated and she had breastfed for 5 months prior to discontinuing due to exhaustion.Investigations showed severe hypercalcaemia (4.94 mmol/l) and undetectable PTH. Hypercalcaemia was unresponsive to...

Introduction: Anti-phospholipid syndrome is characterised by the presence of arterial or venous thrombosis, it is autoimmune in nature and manifests as a systemic disease. Adrenal vein haemorrhagic infarction which is a sequel of adrenal vein thrombosis ultimately leads to loss of adrenal function, it is one of the presentations of anti-phospholipid syndrome especially with catastrophic type. In one analysis adrenal involvement was reported in only 13% of the reported cases of...

Previous studies have shown increased hypoglycemia-associated cardiac arrhythmia and mortality in patients with type 2 diabetes and cardiovascular disease.In this study, we aimed to evaluate the response of gastrointestinal hormones and glucoregulatory hormones to the oral glucose tolerance test in patients who were diagnosed with reactive hypoglycemia and to evaluate the risk of arrhythmia with long-holter ECG measurements in patients with a diagnosis o...